About Us

Mark Iwicki

Chairman and Chief Executive Officer

Mr. Iwicki has served as our Chief Executive Officer and Chairman of our board of directors since September 2015. Previously he served as Executive Chairman of our board of directors from April 2015 to September 2015. Prior to joining us, Mr. Iwicki served as President and Chief Executive Officer of Civitas Therapeutics, Inc., or Civitas, a biopharmaceutical company which was acquired by Acorda Therapeutics, from January 2014 to November 2014.   Read More »


Howard B. Rosen

Board Member

Mr. Rosen has served as a member of our board of directors since January 2014. Since 2008, Mr. Rosen has served as a consultant to several companies in the biotechnology industry. He has also served as a lecturer at Stanford University in Chemical Engineering since 2009 and in Management since 2011. Mr. Rosen served as Chief Executive Officer of AcelRx Pharmaceuticals, Inc., or AcelRx, a public company developing products for pain relief, from April 2016 to March 2017, and Interim Chief Executive Officer from April 2015 to March 2016.   Read More »


Robert Langer, ScD

Co-Founder and Board Member
David H. Koch Institute Professor, MIT

Dr. Langer has served as a member of our board of directors since December 2009. Dr. Langer has been an Institute Professor at the Massachusetts Institute of Technology, or MIT, since 2005, and prior to that was a Professor at MIT since 1977. Dr. Langer received his B.S. from Cornell University and his Sc.D. from MIT both in Chemical Engineering.   Read More »


Chen Yu, MD, MBA

Board Member
Managing Partner, Vivo Capital

Dr. Yu has served as a member of our board of directors since April 2016. Dr. Yu has been a Managing Partner at Vivo Capital LLC, or Vivo, since 2011. Prior to joining Vivo in 2004, Dr. Yu worked at aQuantive, a private technology company.   Read More »


Gregory Grunberg, MD, MBA

Board Member
Managing Director, Longitude Capital

Dr. Grunberg has served as a member of our board of directors since April 2016. Dr. Grunberg has been the Managing Director of Longitude Capital Management Co., LLC, or Longitude, since 2012 and has focused on medical technology and drug development.   Read More »


Paulina Hill, Ph.D.

Board Member
Principal, Polaris Partners

Dr. Hill has served as a member of our board of directors since June 2017. Dr. Hill is a principal at Polaris Partners, or Polaris, where she has been since 2012 and has focused on investments in healthcare. Prior to joining Polaris, Dr. Hill completed her postdoctoral fellowship in the Chemical Engineering department at the Massachusetts Institute of Technology.   Read More »


Rajeev Shah

Board Member
Managing Director & Portfolio Manager, RA Capital

Mr. Shaw has served as a member of our board of directors since July 2015. Mr. Shah is a Managing Director and Portfolio Manager at RA Capital Management, LLC, or RA Capital.   Read More »


Robert Paull

Board Member
Co-Founder and Venture Partner, Lux Capital

Mr. Paull has served as a member of our board of directors since July 2009. Mr. Paull is a Co-founder and Venture Partner at Lux Capital Management, or Lux Capital, where he has been since October 2004 and has focused on ventures in healthcare. In addition to joining Lux Capital, Mr. Paull served as our founding Chief Executive Officer, President and Treasurer from July 2009 to June 2012.   Read More »


Robert Tepper, MD

Board Member
Partner, Third Rock Ventures

Dr. Tepper has served as a member of our board of directors since December 2009. Dr. Tepper is a General Partner of Third Rock Ventures, L.P., or Third Rock, which he co-founded in March 2007 and focuses on the formation, development and scientific strategy of Third Rock’s portfolio companies, as well as actively identifying and evaluating new investments.   Read More »